dealing with anti-spam bounces?

OK most folk who've been following the spam thread probably know how my
anti-spam filter works.

I'd like to know if anybody has any good ideas for handling spam bounces.
ie. bounce messages from my auto-responder hitting bogus addresses.

Do I have to keep track of every spammer I've responded to and trash any
incoming spam bounces?

I my auto reply daemon adds headers in it's responds are any of those
headers guarantted to be returned by the bounce message?