Procmail efficency? How do I make my .procmailrc more efficient?

Specifically, I'm in a quandry about creating complex regex's or individual  
recipies for each item..

Right now I'm using this

:0:
*  
^TO\/(stepwise-talk-request|rhapsody-nda-request|rhapsody-nda|rhapsody-ui|webobjects|spamtools|rhapsody-dev|modperl|stepwise-talk|rhapsody-talk|next-prog|eof|dilbert_nextmail|omniweb-l|procmail|zsh-users|zsh-announce)
{
        FOLDER=`echo $MATCH | tr 'A-Z' 'a-z'`
        :0
        |appnmail $MAILING_LIST_DIRECTORY/$FOLDER
}


to deal with the majority of the mailing lists I have to file

The problem here is that email sent to multiple lists all wind up in the  
first folder..

If I seperates out each test I could handle it much better, making sure each  
copy gets put into its place...

but will it be significantly slower?

I've already dropped all the BODY searches in my spam filters due to the  
slowness on large emails (maybe I should just test for size before testing  
bodies?)